For the first time combined payment with delivery and in turn took away market incentives. The birth of out of control healthcare costs.
Roosevelt cut a deal with bankers whereby they would make more money available but had the ability to choose to whom (what areas) they would lend. Most slums in today's major cities exist because of what Roosevelt allowed the bankers to do.
Enabled those who probably should not own a house to take title of house through easier credit and which contributed to the S&L collapse and then ultimately the realestate bubble and subsequent collapse of the US Economy.